Posts in Uncategorized

Trial: Improving Treatment Options for Hormonal Imbalance Disorders

January 17th, 2020 Posted by Uncategorized 0 thoughts on “Trial: Improving Treatment Options for Hormonal Imbalance Disorders”

1nHealth needs women participants willing to contribute to the advancement of treatment options for disorders linked to the following hormonal imbalances: PCOS, Menopause, Endometriosis. Participants will receive expert care, and compensation is available upon demonstration of protocol compliance throughout the entire study.

Trial: Confirming Efficacy of Antibiotic Therapy for Patients of UTI

January 9th, 2020 Posted by Uncategorized 0 thoughts on “Trial: Confirming Efficacy of Antibiotic Therapy for Patients of UTI”

1nHealth is actively seeking those suffering from the clinical symptoms of a urinary tract infection (UTI) for a research study designed to compare the effectiveness of an investigational medication to the standard treatment.

Trial: Assessing Treatment Efficacy Among Migraine Patients

December 2nd, 2019 Posted by Uncategorized 0 thoughts on “Trial: Assessing Treatment Efficacy Among Migraine Patients”

1nHealth is proud to announce that recruitment is underway for a clinical trial tasked with testing the safety and efficacy of a treatment option designed to benefit migraine sufferers.

Background

A migraine occurs when calcitonin gene-related peptide (CGRP) molecules cause blood vessels to dilate, thereby releasing neurotransmitters that create pain.

Migraines are often associated with forms of depression, and although non-life-threatening, symptoms can be unbearable. Such symptoms include: severe head pain, nausea/vomiting, sensitivity to light, aura (flashes of light, blind spots, etc.), fatigue, and loss of vision/blurred vision.

While there is no known cure for migraines, there is a plethora of treatment options. Unfortunately, no specific treatment option works universally among migraine sufferers, and well over half of these individuals are unsatisfied with their current treatment plan. Therefore, there is a significant need for the development of additional treatments.

Existing Treatment Options

Existing therapies can primarily be sorted into two categories: preventative treatments and acute “relief” treatments. Preventative medications are intended to reduce the occurrence and intensity of migraines, while acute medications are to be taken at the outset of migraine symptoms.

The following table details existing treatments on the market:

Preventative Treatments Acute Treatments
Botox injections – Small injections around the head and neck areas can reduce the frequency of migraines. Triptans – These serotonin receptor agonists are taken orally, via nasal spray, etc., and are effective in relieving migraine symptoms.
Antidepressants – Research suggests that antidepressants containing amitriptyline have the potential to prevent migraines. Pain relievers – Analgesics and NSAIDs (ex. Tylenol) are an effective option for alleviating migraines and typically available over-the-counter.
Anti-seizure drugs – Anticonvulsants housing topiramate or valproate are known to reduce migraine frequency. Dihydroergotamines – To be taken as a nasal spray or injection, dihydroergotamines are most effective if taken once symptoms begin.
CGRP inhibitors – CGRP molecules cause migraine pain; CGRP inhibitors dull the effects of this discomfort. Anti-nausea drugs – Most often combined with pain medications, anti-nausea drugs (chlopromazine) reduce nausea and vomiting.
Beta blockers – Blood-pressure-lowering medications containing propranolol or metoprolol can prevent migraines. Opioids – Often seen as a last resort, opioid medications are dopamine receptor antagonists to be used when other treatments prove to be ineffective.

Study Specifics

The 1nHealth team is recruiting male/female participants, ages 18 to 65, living within a 25-mile radius of Los Alamitos, CA. Potential participants must have at least a one-year history of migraines (with or without aura), according to the International Classification of Headache Disorder.

The study requires one or more visits to a physical site location for physical assessment, and participants will be asked to consume the study product regularly. Compensation is available for those who complete the clinical trial while demonstrating protocol compliance.

Applying to the study is straightforward, quick, and painless. All you’ll need is access to the internet in order to register and complete a brief survey. If you qualify, a member of our study team will contact you to schedule a visit to your nearest clinic location. Interested in learning more? Click the button below.

Trial: Confirming Effectiveness of a Treatment for Irritable Bowel Syndrome

November 20th, 2019 Posted by Uncategorized 0 thoughts on “Trial: Confirming Effectiveness of a Treatment for Irritable Bowel Syndrome”

We’re pleased to announce that recruitment is underway for our latest research study. This randomized, double-blind, placebo-controlled study will measure the effectiveness of a new treatment option in relieving symptoms of Irritable Bowel Syndrome with Diarrhea (IBS-D).

Trial: Comparing Efficacy of Two Treatment Options for Asthma

November 20th, 2019 Posted by Uncategorized 0 thoughts on “Trial: Comparing Efficacy of Two Treatment Options for Asthma”

1nHealth is currently recruiting for a clinical trial tasked with comparing the efficacy of two treatment options intended for adults diagnosed with asthma.This study places an emphasis on exploring the efficacy of a leading branded inhaled corticosteroid compared to that of a pressurized metered-dose inhaler containing fluticasone propionate.

Announcement: Verifying Drug Safety in Kidney Disease Patients

October 28th, 2019 Posted by Uncategorized 0 thoughts on “Announcement: Verifying Drug Safety in Kidney Disease Patients”

It is important to measure effects on the kidney during drug development, as poorly functioning kidneys can cause medicines to accumulate in the body. In addition, certain medications are known cause kidney damage or inhibit kidney function. 1nHealth is currently recruiting for a clinical trial designed to measure the safety of an investigational new drug among kidney disease patients.

Announcement: Assessing Drug Safety Among Liver Disease Patients

October 21st, 2019 Posted by Uncategorized 0 thoughts on “Announcement: Assessing Drug Safety Among Liver Disease Patients”

Medications taken orally pass through the liver, where drug metabolism takes place. During drug development, an importance is placed on testing to ensure that liver damage does not occur during the breakdown process. 1nHealth is currently recruiting late-stage liver disease patients for a clinical trial tasked with confirming the safety of an investigational drug.

Announcement: Fighting Crohn’s Disease with New Treatment Options

October 7th, 2019 Posted by Uncategorized 0 thoughts on “Announcement: Fighting Crohn’s Disease with New Treatment Options”

1nHealth is currently recruiting for numerous clinical trials designed to benefit the Crohn’s community.

Background: Crohn’s Impacts Quality of Life

Crohn’s disease can be described as an bowel disease that causes chronic inflammation of gastrointestinal tract. Crohn’s disease can have a severe impact on the quality of life of most patients. This can be attributed to its common symptoms which include diarrhea, weight loss, and cramping/pain in the abdomen; additional symptoms may include anemia, exhaustion, joint pain, nausea, and even fever. Although doctors cannot yet pinpoint the root cause of the disease, potential contributing factors may include genetics, smoking, an autoimmune reaction, and a high-fat diet.

Call for More Treatment Options

There is currently no known cure for Crohn’s disease, however, various treatment options exist. The need for advancement in available treatment options is made clear when considering that no single treatment works for all Crohn’s patients. The following breakdown details the pain points of conventional treatment options:

  • Medicine – Medication is often the medium by which Crohn’s symptoms (flare-ups) are managed, however many drugs have limitations in what they can accomplish:
    • Aminosalicylates (5-ASA) effectively reduce inflammation in the lining of the GI tract, but are not approved by the FDA and are not recommended for treating Crohn’s disease in the small intestine.
    • Corticosteroids treat moderate to severe Crohn’s disease by suppressing the entire immune response as opposed to focusing on specific components of the immune system; corticosteroids are not a long-term solution.
    • Immunomodulators are known to reduce inflammation in the digestive tract but can take weeks/months benefit the patient, and can result in a low white blood cell count.
    • Biologic Therapies can be described as an option utilized when traditional medications do not suffice. However, such therapies can result in serious infections, including tuberculosis.
  • Bowel Rest – Those with severe symptoms may need to rest their bowels for days/weeks by way of not eating or only consuming certain liquids. It is not uncommon for a patient to receive a feeding tube inserted into their stomach or be required to consume liquids intravenously.
  • Surgery – Surgery cannot cure Crohn’s disease, however about 70 percent of all Crohn’s patients will require surgery when medications fail to curb symptoms. Surgery is deemed necessary should the patient encounter a fistula, fissure, or an intestinal obstruction.

Clinical Trial Nearest You: Benefits and Convenience

What can you expect from the clinical trials for which 1nHealth is currently recruiting? Participants will receive expert care at no cost (transportation costs may be compensated), gain access to new treatment options, and help existing Crohn’s patients.

With more than 40 physical site locations (see below) spread across the U.S., participants will be matched with a clinical trial conducted at a site location nearest to them. Determining initial eligibility is simple, and only requires you answer a few questions… we’ll do the rest.

To gauge initial eligibility, click here.

Physical site locations are listed below:

State City
Arizona Scottsdale, Tempe
California Coronado
Colorado Colorado Springs
Florida Inverness, Kissimmee, Lighthouse Point, Maitland, Miami, Naples, New Port Richey, Orlando, Palmetto Bay, Tampa
Kentucky Lexington, Louisville
Louisiana Baton Rouge, Gretna, Houma, New Orleans, Shreveport
Maryland Chevy Chase
Michigan Ann Arbor
North Dakota Fargo
Ohio Columbus, Dayton, Mentor
Oklahoma Oklahoma City
South Dakota Rapid City
Tennessee Johnson City, Memphis,
Texas Arlington, Houston, San Antonio, Tyler, Victoria
Utah Riverton
West Virginia Morgantown

 

 

Image of a girl using a cellphone to represent the connectivity to help our volunteers

Hello world!

March 12th, 2019 Posted by Uncategorized 1 thought on “Hello world!”

Welcome to WordPress. This is your first post. Edit or delete it, then start writing!