A 2024 analysis published in
eClinicalMedicine examined nearly 800 federally funded clinical trials and found a clear pattern. The harder a consent form was to read, the more patients dropped out. The same analysis found that most consent forms are written above the reading level of the average American adult. The document meant to inform a patient often becomes the first sign that the study was not built with them in mind.
Sponsors frequently treat recruitment and retention as separate efforts, handed to separate teams and solved in sequence. That sequence carries a cost. A faster enrollment curve means little when the patients filling those slots never understood what they signed up for.
At 1nHealth, we treat clarity and fit as the foundation of retention rather than a later repair. When recruitment respects the patient from the first conversation, staying in the study becomes the natural result of work already done.