Living with Bipolar Disorder?
Anyone can struggle with bipolar disorder. Sometimes – even with therapy, medication, and support – depression and suicidal thoughts can become worse. Researchers are currently studying a new investigational medication as part of this clinical trial that may help.
Need immediate help?
Text or call any time, 24/7 to the Suicide & Crisis Lifeline at 988
To find a crisis center near you, try this site: https://twloha.com/find-help/help-by-topic/suicide/
See if You Qualify
Fill out the form below to see if you meet the basic study requirements. Your personal information will only be used for the purposes of the study.
To participate in the study, you will need to:
As a participant, you would get the opportunity to help with important bipolar disorder medication research. The study is designed to assess the ability of an investigational combination of two FDA-approved medications to decrease suicidal thoughts and depression. Compensation is also available for your participation.
Frequently asked questions
Yes, the study requires that you have a diagnosis of bipolar disorder and have tried a medication for bipolar disorder in the past 5 years. You do not need to be taking medication currently or be under psychiatric care currently to qualify.
NRX-101 is a capsule that combines two medications that are already FDA-approved for other uses. The medications are D-cycloserine and lurasidone HCI (commonly used to treat bipolar disorder).
There is no placebo group in this study but there is a control group. The control group will receive only lurasidone, instead of the study drug NRX-101 which combines lurasidone and D-cycloserine.
All study-related care is provided at no cost and travel is reimbursed.
The length of study participation is approximately 10 weeks.
Yes, there is compensation available for participation and travel. Compensation amounts are determined on a site-by-site basis. Please check with your site for more information.
Yes, participation is completely voluntary and can be ended at any time.